| Robert Downey Jr. (Peter Highman) |
| Zach Galifianakis (Ethan Tremblay) |
| Juliette Lewis (Heidi) |
| Michelle Monaghan (Sarah Highman) |
| Jamie Foxx (Darryl) |
| Danny McBride (Lonnie) |
| RZA (L'agent de sécurité) |
| Brody Stevens (Le chauffeur de la limousine) |
| Matt Walsh |
| Jakob Ulrich (Patrick) |
| Naiia Ulrich (Alex) |
| Todd Phillips (Barry) |
| Bobby Tisdale (Carl) |
| Sharon Morris |
| Nathalie Fay |
| Emily Wagner |
| Steven M. Gagnon |
| Paul Renteria |
| Marco Rodríguez |
| Mimi Kennedy (La mère de Sarah) |
| Tymberlee Hill |
| Keegan-Michael Key |
| Aaron Lustig (Le Dr. Greene) |
| Jon Cryer (Alan Harper) |
| Charlie Sheen (Charlie Harper) |
| Haji Abdullah |
| Cesar Aguirre |
| Jeremy Ambler |
| Charley Barksdale |
| Marvel Bell |
| James Belyeu |
| Tina Borek |
| Shannon Brinson |
| Madeline Brumby |
| Peter Choi |
| Sarah Reagin Clemmensen |
| Frances Cobb |
| Kelly Kathleen Dyniewicz-Roberts |
| Kennith Edwards |
| Amy L. Eller |
| Howard Fine |
| Tony Folden |
| Reggie O. Freeman |
| Gilbert Galon |
| Kristol Grant Blanks |
| Joseph Harold |
| Cyrah Hawkins |
| Barry Hopkins |
| Chris Labadie |
| Erica LaRose |
| Kc Lindley |
| Meghan McCarthy |
| Joseph O'Brien |
| Scott M. Yaffee |