| Natasha Henstridge (Sil) |
| Ben Kingsley (Le Dr. Xavier Fitch) |
| Forest Whitaker (Dan Smithson) |
| Michael Madsen (Preston Lennox) |
| Alfred Molina (Le Dr. Stephen Arden) |
| Marg Helgenberger (Le Dr. Laura Baker) |
| Michelle Williams (Sil jeune) |
| Shirley Prestia (Le Dr. Victoria Roth) |
| Scott McKenna |
| Virginia Morris (La mère) |
| David K. Schroeder (Le touriste allemand) |
| Jordan Lund |
| Don Fischer |
| Jayne Luke |
| David Jensen |
| Esther Scott |
| William Utay |
| David Selburg |
| Herta Ware (Mme Morris) |
| Melissa Bickerton |
| Lucy Rodriguez |
| Scott Sproule |
| Stogie Kenyatta |
| Gary Bullock (L'employé du motel) |
| Susan Hauser |
| William Bumiller |
| Caroline Barclay |
| Matthew Ashford |
| Anthony Guidera |
| Sarah S. Leese |
| Whip Hubley (John Carey) |
| Patricia Belcher |
| Richard Fancy |
| Leslie Ishii |
| Marliese K. Schneider |
| Robert Mendelson |
| Pam Cook |
| Lisa Liberati |
| Ed Stone |
| Dendrie Taylor (Marie) |
| Kurtis Burow |
| Dana Hee |
| Frank Welker |
| Justin Armao |
| Andrzej Bartkowiak |
| Jellybean Benítez |
| Greg Bronson |
| Jimmy Chunga |
| Roger Donaldson (Un passant) |
| James Ent (Le Lt. Steele) |
| Roman Güttinger |
| Christopher Ivins |
| Zak Knutson |
| Coati Mundi |
| Jason Newell |
| Michael Satterfield |
| Peter Wick |