| Millicent Simmonds (Rose) |
| Julianne Moore (Lillian Mayhew / Rose) |
| Cory Michael Smith (Walter) |
| James Urbaniak (Le Dr. Kincaid, le père de Rose) |
| Damian Young (Otto, le gardien du musée) |
| Patrick Murney |
| Lauren Ridloff (Pearl) |
| Anthony Natale (Le Dr. Gill) |
| Carole Addabbo (Miss Conrad) |
| Howard Seago (Remy Rubin) |
| Brian Berrebbi |
| John McGinty (Valentin) |
| Mark A. Keeton |
| Patrick Wiley |
| Garrett Zuercher |
| Jared Johnston |
| Murphy Guyer |
| Ekaterina Samsonov (Hannah) |
| Sawyer Niehaus |
| Lilianne Rojek (Florence) |
| Michael W. Gaines |
| Oakes Fegley (Ben) |
| Jaden Michael (Jamie) |
| Michelle Williams (Elaine) |
| Tom Noonan (Walter) |
| Morgan Turner (Janet) |
| Amy Hargreaves (Tante Jenny) |
| Sawyer Nunes (Robbie) |
| Raul Torres |
| Mandela Bellamy |
| Jim Lavin (Le docteur des urgences) |
| Colleen Cosgrove (L'infirmière des urgences) |
| Hays Wellford |
| Asa Liebmann |
| John Boyd (Danny) |
| Oladamolami Adisa |
| Mylo Barrett |
| Robinho Cruz |
| Vanessa DeLeon |
| Jordana Lurman |
| George Aloi (Monsieur Raqueu) |
| Amanda Anthony |
| Marshall Axt |
| Michael Daniel Birnberg |
| Andrew James Bleidner |
| Book Boards |
| Roger Brenner |
| Jeremiah Burch III |
| Marko Caka |
| Mackenzie Grace Castle |
| Derek Chadwick (Liam) |
| Marmee Regine Cosico |
| Ethan Coskay |
| Namaiya Cunningham |
| Blake Alan Deemer |
| Morgen Dukes |
| Clare Louise Frost |
| Michael James Fry |
| Travis Geiger |
| Michael D. Joseph |
| Kaitlyn T. Junas |
| Will MacAdam |
| Ronnie Magri |
| Ren Marsh (M. Coons) |
| Doris McCarthy |
| Kevin D. McGee |
| Connor Moeller |
| Avery Mull |
| Mounir Quazzani |
| Maria Elena Ramirez |
| Morgan Ashley Reichberg |
| Quincy Saadeh |
| Eric Santamaria |
| Michael Schwendemann |
| Nancy Ellen Shore |
| Nadia Sobehart |
| Nigel Swinson |
| Chuck Taber |
| Logan Taylor |
| George J. Vezina |
| Tom Waters |
| Emily Weiner |
| Ashley Wool |